Cooperative Catalytic Reactions Using Organocatalysts and Transition Metal Catalysts: Propargylic Allylation of Propargylic Alcohols with alpha,beta-Unsaturated Aldehydes

作者：Ikeda Masahiro; Miyake Yoshihiro; Nishibayashi Yoshiaki^*

来源：Organometallics, 2012, 31(9): 3810-3813.

DOI：10.1021/om300286b

Propargylic allylation of propargylic alcohols with alpha,beta-unsaturated aldehydes in the presence of a thiolate-bridged diruthenium complex and a secondary amine as cocatalysts has been found to give the corresponding propargylic allylated products, where the gamma-propargylation occurs selectively at the alpha,beta-unsaturated aldehydes, in high yields as a mixture of two diastereoisomers.

• 出版日期2012-5-14