Autism: clinical and neurobiological features, early diagnosis, treatment and some current developments

作者：Korkmaz Baris^*

来源：Turkish Archives of Pediatrics, 2010, 45: 37-44.

• Autism
• clinical features
• early diagnosis
• neurobiological features
• treatment

Aim: The aim of this study is to review the studies about clinical and neurobiological features, early diagnosis and treatment of autism.
Material and Method: A computerized literature search was conducted using PubMed to retrieve studies about clinical and neurobiological features, early diagnosis and treatment of autism in addition to many references given to the textbooks.
Results: Autism is a neurobiological syndrome which has many subtypes through different mechanisms. The severity and the profile of clinical presentation depend on the degree and pervasiveness of involvement of overlapping neuroanatomical circuits. Among the clinical signs are impairment in social interaction and communication and restricted repetitive and stereotyped patterns of behavior, interests, and activities, sensory and behavioral disturbances.
Conclusions: There is no cure for autism and it is a lifelong disorder. Early diagnosis and beginning of early and appropriate educational intervention may improve adaptive skills. (Turk Arch Ped 2010; 45: 80(th) Year: 37-44)

• 出版日期2010-6