Asymmetric Synthesis of (+)- and (-)-Pauciflorol F: Confirmation of Absolute Stereochemistry

作者：Kerr Daniel J; Miletic Michael; Manchala Narasimhulu; White Jonathan M; Flynn Bernard L^*

来源：Organic Letters, 2013, 15(16): 4118-4121.

DOI：10.1021/ol401752u

An efficient, formal enantioselective synthesis of (+)- and (-)-pauciflorol F has been achieved using a recently introduced oxazolidinone controlled torquoselective Nazarov reaction. The absolute stereochemistry of pauciflorol F and its biosynthetic precursors has been unambiguously confirmed using X-ray crystallography.

• 出版日期2013-8-16