A general glycomimetic strategy yields non-carbohydrate inhibitors of DC-SIGN

作者:Garber Kathleen C A; Wangkanont Kittikhun; Carlson Erin E; Kiessling Laura L*
来源:Chemical communications, 2010, 46(36): 6747-6749.
DOI:10.1039/c0cc00830c

摘要

Shikimic acid can be transformed into monovalent and multivalent glycomimetics that target different members of the C-type lectin class, including DC-SIGN, a dendritic cell lectin that facilitates HIV transmission.

  • 出版日期2010