科研之友
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摘要
UV-generated excited states of cytosine (C) nucleobases are precursors to mutagenic photoproduct formation. The i-motif formed from C-rich sequences is known to exhibit high yields of long-lived excited states following UV absorption. Here the excited states of several i-motif structures have been characterized following 267nm laser excitation using time-resolved infrared spectroscopy (TRIR). All structures possess a long-lived excited state of approximate to 300ps and notably in some cases decays greater than 1ns are observed. These unusually long-lived lifetimes are attributed to the interdigitated DNA structure which prevents direct base stacking overlap.
- 出版日期2016-5-4
