An efficient synthetic route to carbocyclic enaminonitriles via Lewis acid catalysed domino-ring-opening-cyclisation (DROC) of donor-acceptor cyclopropanes with malononitrile

作者：Ghorai Manas K^*; Talukdar Ranadeep; Tiwari Deo Prakash

来源：Chemical communications, 2013, 49(74): 8205-8207.

DOI：10.1039/c3cc44533j

A highly efficient strategy for the synthesis of functionalised carbocyclic enaminonitriles in excellent yields has been described. The reaction utilises Yb(OTf)(3) catalysed C-C bond cleavage and two simultaneous C-C bond formations of donor-acceptor (DA)-cyclopr-opanes with malononitrile anions in a domino fashion.

• 出版日期2013