Applications of N '-alkylated derivatives of TsDPEN in the asymmetric transfer hydrogenation of C=O and C=N bonds

作者：Martins Jose E D; Redondo Miguel A Contreras; Wills Martin^*

来源：Tetrahedron: Asymmetry , 2010, 21(18): 2258-2264.

DOI：10.1016/j.tetasy.2010.07.013

Arene/Ru(II) complexes of (R,R)-N-alkyl-TsDPEN ligands are effective in the asymmetric transfer hydrogenation of ketones and imines in formic acid/triethylamine solution. The complex derived from the N'-Bn derivative of TsDPEN reduces monocyclic imines in up to 60% ee, whilst the N'-Me derivative of TsDPEN forms a more active catalyst than the non-alkylated analogue and reduces ketones in up to 97% ee.

• 出版日期2010-9-27