A green one-pot synthesis of spironaphthopyrano [1,2-b]indeno-7,3 '-indolines

作者：Asadi Shima; Ziarani Ghodsi Mohammadi^*; Rahimifard Mahshid; Soorki Ali Abolhassani

来源：Research on Chemical Intermediates, 2015, 41(9): 6219-6227.

DOI：10.1007/s11164-014-1734-2

• Catalyst-free
• Isatin
• Indandione
• Spironaphthopyrano[1,2-b]indeno-7,3 '-indolines

For the first time, spironaphthopyrano[1,2-b]indeno-7,3'-indolines were prepared by cyclo-condensation of 1,3-indandione, isatin, and 2-naphthol under solvent-free and catalyst-free conditions. This procedure is not only environmentally benign but is also a simple, one-pot, three-component procedure with the advantages of easy workup and mild reaction conditions. The same reaction was investigated with other beta-diketones instead of 1,3-indandione, and the results are reported. The compounds synthesized were screened for antimicrobial activity.

• 出版日期2015-9