Adults with congenital heart disease and heart transplantation: Optimizing outcomes

作者：Goldberg Sara W; Fisher Stacy A^*; Wehman Brody; Mehra Mandeep R

来源：Journal of Heart and Lung Transplantation, 2014, 33(9): 873-877.

DOI：10.1016/j.healun.2014.05.001

• adults
• congenital heart disease
• heart transplantation
• outcomes
• morbidity and mortality

The growing population of adults with congenital heart disease (ACHD) present a distinct set of challenges in the evaluation, listing, and safe performance of heart transplantation. We review existing literature to (1) describe the complex anatomic and physiologic features that characterize this group of patients, (2) discuss factors contributing to high waiting list times and waiting list morbidity and mortality experienced by this population, and finally, (3) identify risk factors for the elevated post-transplant morbidity and mortality reported in ACED patients. We conclude with a discussion of critical areas in need of further investigation as well as ways to amend the current listing criteria to better accommodate ACHD patients in need of heart transplantation.

• 出版日期2014-9