Atopic dermatitis: addressing allergy, infection, itch and complementary therapies

作者:Ahluwalia Jusleen; Davis Dawn Marie; Jacob Sharon; Waldman Andrea; Ong Peter Y; Cohen Stuart; Friedman Adam; Lio Peter; Jetter Nathan; Bienstock Jeffrey; LeBovidge Jennifer; Spergel Jonathan; Fonacier Luz*
来源:Seminars in Cutaneous Medicine and Surgery, 2017, 36(3): 112-117.
DOI:10.12788/j.sder.2017.038

摘要

Atopic dermatitis (AD) is a complex condition that results from the dynamic interplay between genetic predisposition, skin barrier defects, environmental factors, and a dysfunctional immune system. As a result, AD can be complicated by irritant and allergic contact dermatitis and imbalances in the skin microbiome, which can subsequently exacerbate the severity and complicate the course of preexisting atopic disease. Itch is an important symptom of AD, as it plays a large role in the quality of life of patients and their families. Since AD is a chronic, inflammatory disease that recrudesces throughout life, many have utilized alternative and/or complementary therapies, as mono therapy or in conjunction with conventional therapies, as a form of management.

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