NIR dyes for bioimaging applications

作者:Escobedo Jorge O; Rusin Oleksandr; Lim Soojin; Strongin Robert M*
来源:Current Opinion in Chemical Biology, 2010, 14(1): 64-70.
DOI:10.1016/j.cbpa.2009.10.022

摘要

Fluorescent dyes based on small organic molecules that function in the near infrared (NIR) region are of great current interest in chemical biology. They allow for imaging with minimal autofluorescence from biological samples, reduced light scattering, and high tissue penetration. Herein, examples of ongoing NIR fluorophore design strategies as well as their properties and anticipated applications relevant to the bioimaging are presented.

  • 出版日期2010-2