Abyssomicin E, a highly functionalized polycyclic metabolite from Streptomyces species

作者:Niu Xue Mei*; Li Sheng Hong; Goerls Helmar; Schollmeyer Dieter; Hilliger Matthias; Grabley Susanne; Sattler Isabel
来源:Organic Letters, 2007, 9(13): 2437-2440.
DOI:10.1021/ol0705999

摘要

Abyssomicin E (1), a new polycyclic metabolite with a C19 skeleton, was isolated from Streptomyces sp. (HKI0381). Its chemical structure was determined by comprehensive NMR and MS spectroscopic analyses. For the first time in this recently discovered class of compounds, the absolute stereochemistry was directly established by subsequent single-crystal X-ray diffraction study using anomalous dispersion with copper radiation.

  • 出版日期2007-6-21