Nanoparticle-based electrochemical detection in conventional and miniaturized systems and their bioanalytical applications: A review

作者：Siangproh Weena; Dungchai Wijitar; Rattanarat Poomrat; Chailapakul Orawon^*

来源：Analytica Chimica Acta, 2011, 690(1): 10-25.

DOI：10.1016/j.aca.2011.01.054

• Metal nanoparticles
• Electrochemical Sensors
• Miniaturized Systems
• Immunosensors
• Biosensors

With recent advances in nanotechnology making more easily available the novel chemical and physical properties of metal nanoparticles (NPs), these have become extremely suitable for creating new sensing assays. Many kinds of NPs, including metal, metal-oxide, semiconductor and even composite-metal NPs, have been used for constructing electrochemical sensors. This article reviews the progress of NP-based electrochemical detection in recent applications, especially in bioanalysis, and summarizes the main functions of NPs in conventional and miniaturized systems. All references cited here generally show one or more of the following characteristics: a low detection limit, good signal amplification and simultaneous-detection capabilities.

• 出版日期2011-3-25