Antimicrobial silver (I) complexes derived from aryl-benzothiazoles as turn-on sensors: Syntheses, properties and density functional studies

作者：Stenger Smith Jenny; Chakraborty Indranil; Sameera W M C; Mascharak Pradip K^*

来源：Inorganica Chimica Acta, 2018, 471: 326-335.

DOI：10.1016/j.ica.2017.11.022

• Benzothiazoles
• Silver complexes
• Fluorescence turn-ON
• Theoretical studies
• Antibacterial

Two Ag(I) complexes derived from 2-(pyridyl) benzothiazole (pbt) and 2-(quinolyl) benzothiazole (qbt) namely, [Ag(pbt)(2)] BF4 (1) and [Ag(qbt)(2)] BF4 (2) have been synthesized and structurally characterized. The Ag(I) center in both complexes are distorted tetrahedral and both ligands bind silver in the N, N-bidentate mode. Upon complexation, the fluorescence of both ligands is quenched significantly and it is restored gradually upon release of silver under biological conditions. Results from theoretical studies indicate that a facile 1MLCT -> (LC)-L-3 (a 1S -> T1 intersystem crossing) transition is responsible for the diminution of the luminescence in these complexes of silver (a heavy metal with high spin-orbit coupling). Both complexes exhibit antibacterial properties toward Gram-positive and Gram-negative bacteria. The bactericidal effect of the complexes is accompanied by an enhancement in fluorescence due to silver delivery to the target bacteria. Published by Elsevier B.V.

• 出版日期2018-2-24