Asymmetric cross- and self-aldol reactions of aldehydes in water with a polystyrene-supported triazolylproline organocatalyst

作者：Llanes Patricia; Sayalero Sonia; Rodriguez Escrich Carles; Pericas Miquel A^*

来源：Green Chemistry, 2016, 18(12): 3507-3512.

DOI：10.1039/c6gc00792a

A polystyrene (PS) immobilized triazolylproline has been prepared by a bottom-up approach involving co-polymerization with full regiocontrol. The resulting PS resin swells in water and has been applied to the enantioselective cross-aldol reaction and to the self-aldol reaction of aldehydes under essentially neat conditions, excellent yields and stereoselectivities being recorded.

• 出版日期2016