An Electrochemical Sensor Based on Ni(II) Complex and Multi Wall Carbon Nano Tubes Platform for Determination of Glucose in Real Samples

作者：Rezaeinasab Masoud; Benvidi Ali; Tezerjani Marzieh Dehghan; Jahanbani Shahriar; Kianfar Ali Hossein; Sedighipoor Maryam

来源：Electroanalysis, 2017, 29(2): 423-432.

DOI：10.1002/elan.201600162

• Glucose
• Modifier
• Carbon paste electrode
• Carbon nanotubes
• Electro oxidation
• Electrochemical techniques

In the present paper, a stable and selective non-enzymatic sensor is reported for determination of glucose (Glc) by using a carbon paste electrode modified with multiwall carbon nanotubes and Ni(II)-SHP complex as modifier in an alkaline solution. This modified electrode showed impressive activity for oxidation of glucose in NaOH solution. Herein, Ni(II)-SHP acts as a suitable platform for oxidation of glucose to glucolactone on the surface of the modified electrode by decreasing the overpotential and increasing in the current of analyte. Under the optimum conditions, the rate constant and electron transfer coefficient between electrode and modifier, were calculated to be 1.04s(-1) and 0.64, respectively. The anodic peak currents indicated a linear dependency with the square root of scan rate and this behavior is the characteristic of a diffusion controlled process. So, the diffusion coefficient of glucose was found to be 3.12x10(-6)cm(2)s(-1) due to the used number of transferred electron of 1. The obtained results revealed two linear ranges (5 to 190.0M (R-2=0.997), 210.0 to 700.0M (R-2=0.999)) and the detection limit of 1.3M for glucose was calculated by using differential pulse voltammetry (DPV) method. Also, the designed sensor was used for determination of glucose in the blood serum and urine samples. Some other advantages of Ni(II)-SHP/CNT/CPE sensor are remarkable reproducibility, stability and selectivity which can be related to using nanomaterial of carbon nanotubes due to enhancement of electrode surface area.

• 出版日期2017-2