Nicotinohydrazide

作者：Priebe Jacks P; Mello Renata S; Nome Faruk; Bortoluzzi Adailton J^*

来源：Acta Crystallographica Section E-Structure Reports Online, 2008, 64: O302-U5353.

DOI：10.1107/S160053680706655X

The title molecule (alternative name: pyridine-3-carbohydrazide; C6H7N3O) was obtained from the reaction of ethyl nicotinate with hydrazine hydrate in methanol. In the amide group, the C-N bond is relatively short, suggesting some degree of electronic delocalization in the molecule. The stabilized conformation may be compared with those of isomeric compounds picolinohydrazide (pyridine-2-carbohydrazide) and isonicotinohydrazide (pyridine-4-carbohydrazide). In the title isomer, the pyridine ring forms an angle of 33.79 (9)degrees with the plane of the non-H atoms of the hydrazide group. This lack of coplanarity between the hydrazide functionality and the pyridine ring is considerably greater than that observed in isonicotinohydrazide (dihedral angle = 17.14 degrees), while picolinohydrazide is almost fully planar. The title isomer forms intermolecular N-H center dot center dot center dot O and N-H center dot center dot center dot N hydrogen bonds, which stabilize the crystal structure.

• 出版日期2008-1