Understanding Population-Based Site-Specific Cancer Incidence Rates in the USA

作者：Merrill Ray M^*; Sloan Arielle; Novilla Lelinneth B

来源：Journal of Cancer Education, 2012, 27(2): 263-268.

DOI：10.1007/s13187-011-0266-3

• Cancer
• Population
• Based incidence rates
• SEER
• Trends
• Prevalence

As compared with conventionally reported national population-based incidence rates, incidence rates better represent the %26quot;burden%26quot; of disease if they remove prevalent cases from the denominator. In order to reflect the %26quot;risk%26quot; in a disease-free population, rates should both exclude prevalent cases from the denominator and second or later diagnosed cases at the same site from the numerator. Five common cancers were evaluated through a correction method using 2005-2007 Surveillance, Epidemiology, and End Results Program data to determine the extent of difference between conventional and corrected incidence rates. These corrections lowered the incidence rates 4.0-5.8% for female breast cancer, 4.6-7.6% for melanoma, 3.0-4.0% for colorectal cancer, and 2.1-2.5% for lung and bronchus cancer. Corrected incidence rates for prostate cancer were 9.9-13.7% higher. In cancers with either high prevalence and/or high occurrence of multiple primaries at the same site, corrected population-based incidence rates are warranted.

• 出版日期2012-6