A Novel Staphylococcal Cassette Chromosomal Element, SCCfusC, Carrying fusC and speG in Fusidic Acid-Resistant Methicillin-Resistant Staphylococcus aureus

作者：Lin Yu Tzu; Tsai Jui Chang; Chen Hsiao Jan; Hung Wei Chun; Hsueh Po Ren; Teng Lee Jene^*

来源：Antimicrobial Agents and Chemotherapy, 2014, 58(2): 1224-1227.

DOI：10.1128/AAC.01772-13

A high prevalence of fusC (16/46, 59%) was found in fusidic acid- resistant methicillin- resistant Staphylococcus aureus isolates collected from 2008 to 2010. Nucleotide sequencing of fusC and flanking regions revealed a novel staphylococcal cassette chromosome (SCC) structure, SCCfusC, which was integrated into rlmH and located upstream from SCCmec. The SCCfusC element contained speG, which may contribute to the polyamine resistance.

• 出版日期2014-2