Determination of the stereochemistry of hydride transfer from NADPH to FAD catalyzed by VlmR, a flavin reductase from the valanimycin biosynthetic pathway

作者：Skae P; Parry RJ^*

来源：Organic Letters, 2001, 3(8): 1117-1119.

DOI：10.1021/ol000389v

The stereospecificity of hydride transfer from NADPH to FAD catalyzed by VImR, a flavin reductase from the valanimycin biosynthetic pathway has been determined. By using stereospecifically deuterated NADPH, it has been shown that the 4-pro R hydrogen of NADPH is transferred.

• 出版日期2001-4-19