A novel self-terminated Prins strategy for the synthesis of tetrahydropyran-4-one derivatives and their behaviour in Fisher indole synthesis

作者：Reddy B V Subba; Anjum S Rehana; Sridhar B

来源：RSC Advances, 2016, 6(79): 75133-75137.

DOI：10.1039/c6ra11218h

A novel self-terminated Prins strategy has been developed for the synthesis of 2-substituted tetrahydropyran-4-one derivatives through a condensation of 3-(phenylthio)but-3-en-1-ol with carbonyl compounds in the presence of 5 mol% of Sc(OTf)3 under mild conditions.

• 出版日期2016