摘要
A chromatographic purification free rapid oligosaccharide synthetic strategy was developed. The intermediates were conveniently purified by a new process based on a capture-release strategy on a resin that involved the Co-2(CO)(6)-PPh2/alkyne complex and the oxidated de-complex reaction. This method avoids the redundant multi-step classical chromatographic purification protocol and has been proved to be efficient by the synthesis of linear and branched penta-mannosides.
- 出版日期2018-7-7
- 单位北京大学; 天然药物与仿生药物国家重点实验室