科研之友
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摘要
In this paper, indium vanadate (InVO4) nanoribbons were obtained by a facile hydrothermal process and were confirmed to have an affinity for hemoglobin (Hb) for the first time: ultraviolet-visible absorption and photoluminescence spectroscopy indicated an interaction between InVO4 and porphyrin, as well as the tryptophan (Trp) and tyrosine (Tyr) residues in Hb; and partial unfolding of the Hb alpha-helix was testified by circular dichroism spectra. Based on the interaction between InVO4 and Hb, InVO4 was employed to modify a glassy carbon electrode, which displayed excellent electrochemical sensitivity in detecting Hb. A linear relationship between the concentration of Hb and its reduction peak currents was obtained. The modified electrode exhibited high reproducibility and stability, which might find potential applications in biosensors.
- 出版日期2012
- 单位苏州大学
