Antiplatelet Drugs: What Comes Next?

作者：Kei Anastazia A; Florentin Matilda; Mikhailidis Dimitri P; Elisaf Moses S; Liberopoulos Evangelos N^*

来源：Clinical and Applied Thrombosis/Hemostasis, 2011, 17(1): 9-26.

DOI：10.1177/1076029610385222

• antiplatelets
• cangrelor
• elinogrel
• PAR-1 inhibitors
• prasugrel
• thienopyridines
• thromboxane inhibitors
• ticagrelor

Antiplatelet drugs are important components in the management of atherothrombotic vascular disease. However, several limitations restrict the safety and efficacy of current antiplatelet therapy in clinical practice. Interpatient variability and resistance to aspirin and/or clopidogrel has spurred efforts for the development of novel agents. Indeed, several antiplatelet drugs are at various stages of evaluation; those at advanced stage of development are the focus of this review.

• 出版日期2011-2