A New Dibenzofuran and Further Constituents from the Stems of Pourthiaea lucida with Inhibitory Activity on Superoxide Generation by Neutrophils

作者：Chen Jih Jung^*; Luo Yu Ting; Liao Chang Hui; Chen Ih Sheng; Liaw Chih Chuang

来源：Chemistry and Biodiversity, 2009, 6(5): 774-778.

DOI：10.1002/cbdv.200800118

A new dibenzofuran, lucidafuran (1), was isolated from the stems of Pourthiaea lucida, together with eight known compounds. The structure of this new compound was determined through NMR and mass-spectrometric analyses. Among the isolated compounds, lucidafuran (1) and aucuparin (3) exhibited potent inhibitory activity against fMLP-induced superoxide (O(2)(center dot-)) production by human neutrophils with IC(50) values of 18.7 /- 4.4 and 17.0 /- 6.8 mu M, resp.

• 出版日期2009
• 单位长春大学; 中国医科大学