A Four Components, One-Pot Synthesis of New Imidazole Molecular Tweezers Based on 2,4,6-Triarylpyridine as Hinge Region

作者：Moghaddam Amini Zahra; Behmadi Hossein^*; Poormorteza Narges; Beyramabadi Safar Ali; Nezhad Arian Maryam

来源：Iranian Journal of Chemistry and Chemical Engineering (International English Edition), 2017, 36(1): 11-18.

• Bis-imidazole
• One-pot reaction
• Triaryl pyridine
• Heterocycles
• Molecular tweezers

In the present study, some new bis-imidazole derivatives have been prepared through four-components condensation of 2,6-bis (4-aminophenyl)-4-p-tolylpyridine, benzaldehyde derivatives, benzil and ammonium acetate in presence of acetic acid. The present methodology offers several advantages such as good yields, simple procedure, milder conditions and the possibility of introducing a variety of substituents at different positions of the imidazole and pyridine rings. These new compounds were confirmed by spectral methods H-1 NMR, C-13 NMR, FT-IR, and elemental analyses. Also, optimized geometries and chemical shifts have been calculated for the synthesized compounds using Density Functional Theory (DFT) method. Their optimized geometries are not planar.

• 出版日期2017