Bone Marrow Enhancement During Time-Resolved Magnetic Resonance Angiography of the Pelvis

作者：Allen Brian C^*; Bashir Mustafa R; Dale Brian M; Heye Tobias J; Gupta Rajan T; Merkle Elmar M

来源：Journal of Computer Assisted Tomography, 2013, 37(3): 458-462.

DOI：10.1097/RCT.0b013e318283d549

• anemia
• bone marrow
• magnetic resonance angiography
• magnetic resonance imaging
• perfusion

Objective: This study aimed to determine whether visible bone marrow enhancement (BME) at pelvic magnetic resonance angiography (MRA) correlates with anemia. %26lt;br%26gt;Methods: This is an institutional review board-approved, Health Insurance Portability and Accountability Act-compliant retrospective study. Seventy-five female patients with a hemoglobin (Hb) test within 10 days of an MRA examination of the pelvis are included, mean age of 46 years (range, 18-81 years). The BME was graded using a 4-point scale. Fifteen subjects had sufficient imaging data for calculation of quantitative perfusion parameters. Receiver operating characteristic and analysis of covariance were performed for 2 levels of anemia. %26lt;br%26gt;Results: Enhancement was visually present in 44% (33/75) of cases; 66% (19/29) of anemic subjects (Hb %26lt; 12 g/dL), and 30% (14/46) of nonanemic subjects (P = 0.002). Enhancement had a sensitivity of 87.5% and a specificity of 92.5% for the diagnosis of severe anemia (Hb %26lt; 10 g/dL); 88% (7/8) of these subjects had moderate to marked enhancement. A high extraction coefficient (K-ep ) in the iliac crest was associated with anemia, with an area under the curve of the receiver operating characteristic of 0.85 for mild anemia and 0.92 for severe anemia. %26lt;br%26gt;Conclusions: Visible BME during time-resolved MRA is common and may be related to anemia.

• 出版日期2013-6