摘要

Introduction: Climate change is considered a direct or indirect contributing factor of cerebrovascular disease. However, there is controversy over the association between climate changes and the occurrence of acute ischemic stroke (AIS). This study was to explore correlations between the occurrence of AIS and seasonal changes. @@@ Materials and methods: This study propose a new way of combine pentad temperature method (classified as the daily mean temperature up to the required temperature for five consecutive days) with circular analysis to analyzed clinical data of 1,587 patients who were diagnosed as MS during three consecutive years to explore correlations between AIS occurrence and seasonal changes. @@@ Results: The circular distribution of monthly MS occurrence showed the mean angle was 100.43 +/- 155.27, and the mean angle 95% confidence interval (CI) was 82.28-190.15; the circular distribution of different AIS subtypes showed only small artery occlusion subtypes showed the mean angle was 88.05 +/- 125.42, and the mean angle 95% CI was 38.30-137.75. @@@ Conclusion: The AIS peak occurrence day was around April 12 (a period from the end of winter to the middle of summer). Only small-artery occlusion showed a central tendency and the peak occurrence day was around March 31 (a period from the end of winter to the beginning of summer).