Absolute configuration of a rare dibenzoylmethane derivative from Dahlstedtia glaziovii (Fabaceae)

作者：Canzi Edione F; dos Santos Fernando M Jr; Meneghetti Emanuelle K; Sales Maia Beatriz Helena L N; Batista Joao M Jr^*

来源：Tetrahedron Letters, 2018, 59(2): 135-137.

DOI：10.1016/j.tetlet.2017.12.002

• Natural products
• VCD
• Exciton chirality
• DFT

Dibenzoylmethanes (DBMs) belong to a small group of flavonoids, known as beta-hydroxychalcones, rarely found in nature. Despite their biological and chemotaxonomic importance, the absolute configuration of C-8 substituted DBMs has never been reported. Herein, the absolute stereochemistry of 2'-methoxy-8-(alpha-alpha-dimethylallyl)-[3',4':4 '',5 '']-furan-dibenzoylmethane is determined using the VCD exciton chirality method, which may be safely applied to other members of this class.

• 出版日期2018-1-10