Design, Synthesis, Characterization, and Antimicrobial Evaluation of Novel 2-(3, 5-di methoxy-4-((1-aryl-1H-1, 2, 3-triazole-4-yl) methoxy) phenyl) benzo[d]thiazoles

作者：Subhashini N J P^*; Chinthala Sravanthi; Raj Shiva

来源：Journal of Heterocyclic Chemistry, 2018, 55(1): 251-257.

DOI：10.1002/jhet.3033

A series of 12 new 2-(3, 5-dimethoxy-4-((1-Aryl-4H-1, 2, 3-triazol-4-yl) methoxy) phenyl) benzo[d]thiazoles have been synthesized from the reaction of 4-hydroxy-3, 5-dimethoxybenzaldehyde, o-amino thiophenol, propargyl bromide, and different substituted aromatic azides using click chemistry. The structures of these compounds were established on the basis of Fourier Transform infrared, H-1 NMR, C-13-NMR, and mass spectral analysis. Compounds (6a-l) were screened for in vitro antimicrobial activity.

• 出版日期2018-1