Base and ligand free copper-catalyzed N-arylation of 2-amino-N-heterocycles with boronic acids in air

作者:Rao D Nageswar*; Rasheed Sk; Aravinda S; Vishwakarma Ram A; Das Parthasarathi
来源:RSC Advances, 2013, 3(29): 11472-11475.
DOI:10.1039/c3ra40735g

摘要

A wide range of N-arylated 2-amino-N-heterocycles were synthesized by a copper-catalyzed boronic acid cross coupling reaction at ambient temperature in air. This ligand and base free methodology is general and could provide rapid access to a diverse array of potential bioactive heterocyclic compounds.

  • 出版日期2013