Anterior cervical discectomy and fusion may be more effective than anterior cervical corpectomy and fusion for the treatment of cervical spondylotic myelopathy

作者：Guan, Li; Hai, Yong; Yang, Jin-Cai; Zhou, Li-Jin; Chen, Xiao-Long^*

来源：BMC Musculoskeletal Disorders, 2015, 16(1): 29.

DOI：10.1186/s12891-015-0490-9

• Anterior cervical corpectomy and fusion
• Anterior cervical discectomy and fusion
• Cervical spondylotic myelopathy
• Meta-analysis

Background: This meta-analysis explored the efficacy and safety of anterior cervical corpectomy and fusion (ACCF) comparing to anterior cervical discectomy and fusion (ACDF) in treating cervical spondylotic myelopathy (CSM) patients. @@@ Methods: Several electronic databases were searched combined with manually searching. Thirteen randomized controlled studies were enrolled with 1,062 CSM patients, including 468 patients and 594 patients in the in the ACCF and ACDF group, respectively. The meta-analysis was then performed using the STATA 12.0 software. Crude standard mean difference (SMD) or odds ratio (OR) with their 95% confidence intervals (CI) were calculated. @@@ Results: Our meta-analysis results revealed that CSM patients in ACDF group showed less blood loss than those in ACCF group (SMD = 1.21, 95% CI = 1.03 similar to 1.39, P < 0.001). The operation time of CSM patients in the ACDF group was also obviously shorter than those in ACCF group (SMD = 0.40, 95% CI = 0.23 similar to 0.57, P < 0.001). Furthermore, CSM patients in ACDF group had shorter hospital time than those in ACCF group (SMD = 0.45, 95% CI = 0.21 0.69, P < 0.001). @@@ Conclusion: Our findings provide empirical evidence that ACDF may be more effective than ACCF for CSM treatment.

• 出版日期2015-2-13
• 单位首都医科大学