A Novel Synthesis of N-But-3-enyl-alpha- and beta-Amino Acids

作者：Van Nguyen T T^*; Brownlee Robert T C; Hughes Andrew B

来源：Synthesis, 2009, 2009(12): 1991-1998.

DOI：10.1055/s-0028-1088072

• 1,3-oxazolidin-5-ones
• 1,3-oxazinan-6-ones
• amino acids
• allylations
• Lewis acids

N-But-3-enyl-alpha- and beta-amino acids can be prepared by cleaving 1,3-oxazolidin-5-ones and 1,3-oxazinan-6-ones in the presence of allylsilanes and boron trifluoride etherate at room temperature in good to excellent yields.

• 出版日期2009-6-17