Stability of Silk Fibroin-Gold Nanoparticles Composite System

作者：Guo Li; Zhu Jingxin^*; Jia Lan; Ke Jing; Ji Lijing

来源：Rare Metal Materials and Engineering, 2016, 45(1): 217-221.

• silk fibroin
• gold nanoparticles
• stability

Highly stable silk fibroin-gold nanoparticles (SF-Au NPs) was obtained using regenerated protein silk fibroin (SF) to stabilize gold nanoparticles (Au NPs), which were prepared through a citrate reduction method. The stability of SF-Au NPs in buffer solutions with different pH conditions and different KCl concentrations were investigated. Ultraviolet-visible spectroscopy (UV-Vis), transmission electron microscopy (TEM) and fourier transform infrared spectroscopy (FTIR) were employed to characterize the SF-Au NPs system. The results reveal that SF-Au NPs possess remarkable stability in the pH range from 3 to 11 and salt concentrations range from 50 mmol/L to 1000 mmol/L. Taking citrate and BSA stabilized gold nanoparticles as comparison, the results indicate that steric hindrance may play a dominated role for the stability of SF-Au NPs. The proposed method is simpler, more efficient, and more cost effective than the conventional modification strategies for Au NPs.

• 出版日期2016-1
• 单位太原理工大学