First Proposal of Minimum Information About a Cellular Assay for Regenerative Medicine

作者：Sakurai Kunie; Kurtz Andreas; Stacey Glyn; Sheldon Michael; Fujibuchi Wataru^*

来源：Stem Cells Translational Medicine, 2016, 5(10): 1345-1361.

DOI：10.5966/sctm.2015-0393

• Stem cells
• Information sharing
• Biological specimen banks
• Standards
• Regenerative medicine
• Quality control

Advances in stem cell research have triggered scores of studies in regenerative medicine in a large number of institutions and companies around the world. However, reproducibility and data exchange among laboratories or cell banks are constrained by the lack of a standardized format for experiments. To enhance information flow in stem cell and derivative cell research, here we propose a minimum information standard to describe cellular assay data to facilitate practical regenerative medicine. Based on the existing Minimum Information About a Cellular Assay, we developed Minimum Information About a Cellular Assay for Regenerative Medicine (MIACARM), which allows for the description of advanced cellular experiments with defined taxonomy of human cell types. By using controlled terms, such as ontologies, MIACARM will provide a platform for cellular assay data exchange among cell banks or registries that have been established at more than 20 sites in the world.

• 出版日期2016-10