Prolonged Complete Response in a Pediatric Patient With Primary Peripheral T-Cell Lymphoma of the Central Nervous System

作者：Shalabi Haneen^*; Angiolillo Anne; Vezina Gilbert; Rubenstein James L; Pittaluga Stefania; Raffeld Mark; Marcus Leigh

来源：Pediatric Hematology and Oncology, 2015, 32(8): 529-534.

DOI：10.3109/08880018.2015.1074325

• CNS tumors
• NHL
• therapy

We describe a child with a 2-week history of progressive headaches, blurry vision, and intermittent vomiting. Magnetic resonance imaging (MRI) of the brain showed a deep left hemispheric lesion with extension into the corpus callosum. Histology and immunophenotyping of the lesion was consistent with peripheral T-cell lymphoma, not otherwise specified. Chemotherapy was initiated and a complete remission was achieved. This case illustrates that a chemotherapeutic regimen used in adults with central nervous system (CNS) lymphoma can achieve durable remissions in pediatric patients with peripheral T-cell lymphoma, not otherwise specified of the CNS.

• 出版日期2015-11-17
• 单位NIH