Herpes Simplex Encephalitis during Treatment with Tumor Necrosis Factor-alpha Inhibitors

作者：Bradford Russell D^*; Pettit April C; Wright Patty W; Mulligan Mark J; Moreland Larry W; McLain David A; Gnann John W; Bloch Karen C

来源：Clinical Infectious Diseases, 2009, 49(6): 924-927.

DOI：10.1086/605498

We report 3 cases of herpes simplex virus encephalitis in patients receiving tumor necrosis factor-alpha (TNF-alpha) inhibitors for rheumatologic disorders. Although TNF-alpha inhibitors have been reported to increase the risk of other infectious diseases, to our knowledge, an association between anti-TNF-alpha drugs and herpes simplex virus encephalitis has not been previously described.

• 出版日期2009-9-15