Aspergivones A and B, two new flavones isolated from a gorgonian-derived Aspergillus candidus fungus

作者:Ma, Jie; Zhang, Xiu-Li; Wang, Yu; Zheng, Ji-Yong*; Wang, Chang-Yun; Shao, Chang-Lun*
来源:Natural Product Research, 2017, 31(1): 32-36.
DOI:10.1080/14786419.2016.1207073

摘要

Two new flavones, aspergivones A (1) and B (2), were isolated from the fungus Aspergillus candidus cultured from the gorgonian coral Anthogorgia ochracea collected from the South China Sea. The structures of 1 and 2 were elucidated by NMR and MS methods and comparison with relatively known compounds. Only 2 showed slight inhibitory activity against alpha-glucosidase with an IC50 value of 244g/mL. Compounds 1 and 2 were also evaluated for their cytotoxic and antibacterial activities.