A New Convenient Synthesis of 2,4-Disubstituted-1,2,4-triazolo[1,5-a]quinazolin-5(4H)-ones

作者:Shawali Ahmad S*; Hassaneen Hamdi M; Shurrab Nabil Kh
来源:Journal of Heterocyclic Chemistry, 2008, 45(6): 1825-1829.
DOI:10.1002/jhet.5570450642

摘要

A novel series of 2,4-disubstituted-1,2,4-triazolo[1,5-a]quinazolin-5(4H)-ones were prepared by Dimroth rearrangement of their respective isomers namely 1,4-disubstituted-[1,2,4]triazolo[4,3-a]-quinazolin-5(4H)-ones. The latter were prepared via new synthetic strategy based on 1,5-elecrocyclization of the respective N-(4-oxo-3-phenylquinazolin-2-yl)nitrilimines.

  • 出版日期2008-12