Anti-ganglioside antibodies in patients with Guillain Barre syndrome and other neurological disorders

作者：Vaishnavi C^*; Behura C; Prabhakar S; Sharma A; Kharbanda P

来源：Indian Journal of Medical Microbiology, 2013, 31(2): 177-179.

DOI：10.4103/0255-0857.115223

• Anti-ganglioside antibodies
• Campylobacter jejuni
• electrophysiological studies
• Guillain-Barre syndrome

A study was performed on 59 Guillain-Barre syndrome (GBS) cases, 58 neurological controls (NC) and 60 non-neurological controls (NNC) to investigate the association of anti-ganglioside antibodies in GBS and other neurological disorders. Campylobacter jejuni was isolated from 5.7% of GBS patients. Anti-ganglioside immunoglobulin G was present in 82% and immunoglobulin M in 46% in acute inflammatory demyelinating polyneuropathy patients, 70% and 44% respectively in acute motor axonal neuropathy subgroup and 38% each in acute motor sensory axonal neuropathy subgroup. Though high intensity of anti-gangliosides was present in the GBS patients, the NC patients also had adequate anti-gangliosides compared with the NNC group.

• 出版日期2013-6
• 单位河北医科大学