NIS-Mediated Oxidative Lactonization of 2-Arylbenzoic Acids for the Synthesis of Dibenzopyranones under Metal-Free Conditions

作者：Gao Peng; Wei Yunyang^*

来源：Synthesis, 2014, 46(3): 343-347.

DOI：10.1055/s-0033-1338568

• lactones
• oxidation
• carboxylic acids
• cyclization
• radical reaction

A series of dibenzopyranones were synthesized from 2-arylbenzoic acids by a radical oxidative cyclization procedure mediated by N-iodosuccinimide (NIS). The methodology is distinguished by its practicality in terms of its wide substrate scope, good functional group tolerance, and mild reaction conditions without the use of transition metals.

• 出版日期2014-2
• 单位南京大学