摘要
Three new dihydro-beta-agarofuran polyesters, 1 alpha,9 beta-difuranoyloxy-2-oxodihydro-beta-agarofuran (1), 1 alpha,9 beta-difuranoyloxy-2-oxo-3-enedihydro-beta-agarofuran (2), and 1 alpha,9 beta-difuranoyloxydihydro-beta-agarofuran (3), have been isolated from the CHCl(3) extract of the root bark of Osyris lanceolata, together with two known pentacylic triterpenoids, 4 and 5. Compounds 1-5 did not scavenge the DPPH radical within 30 min of reaction time. All five compounds displayed antifungal activity against Candida albicans. Compounds 1, 3, 4, and 5 showed antibacterial activity against the Gram-positive Bacillus subtilis and Staphylococcus aureus and Gram-negative Escherichia coli and Pseudomonas aeruginosa, with 4 and 5 being the most active. Compound 2 displayed weak antibacterial activity only against Escherichia coli.
- 出版日期2010-6