科研之友
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摘要
N-Boc-protected serine and threonine esters could be readily added to 2-nitroglycals, affording exclusively a- and beta-anomers with galacto- and gluco-configuration, respectively. Nitro group reduction to the amino group and also ester cleavage led to compounds 2, 6, and 11, which can be regarded as dipeptide mimetics. From these compounds, bicyclic pyrano[2.3-b][1,5]oxazepines 714 were prepared by ring closure.
- 出版日期2011-12
