A girl with extremely refractory Kawasaki disease: an instructive case with unusual course and outcome

作者:Lydia Kossiva*; Evangelos Karanassios; George Papadopoulos; Kyriaki Karavanaki
来源:Cardiology in the Young, 2012, 22(4): 461-465.
DOI:10.1017/S1047951111001260

摘要

Kawasaki disease constitutes an acute febrile vasculitis of unknown aetiology. It is considered the most common cause of acquired cardiac failure in children. Although standard treatment comprises intravenous immunoglobulin and aspirin, some children exhibit refractory disease, necessitating the use of alternative therapies such as corticosteroids and anti-tumour necrosis factor-alpha. For these cases, few controlled data are available. This report focuses on an extremely refractory classical Kawasaki disease with coronary artery aneurysms and ongoing inflammation. We discuss the therapeutic approaches and the potential pitfalls undertaken, which led to an unfavourable clinical outcome.

  • 出版日期2012-8

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