Emergence of oseltamivir-resistant influenza A H1N1 virus during the 2007-2008 winter season in Luxembourg: Clinical characteristics and epidemiology

作者:Mossong Joel*; Opp Matthias; Gerloff Nancy; Hau Patrick; Kremer Jacques; Lackenby Angie; Gregory Vicki; Even Jos; Huberty Krau Pierrette; Muller Claude P; Schneider Francois
来源:Antiviral Research, 2009, 84(1): 91-94.
DOI:10.1016/j.antiviral.2009.08.001

摘要

Human cases of oseltamivir-resistant influenza A H1N1 virus emerging in 2007-2008 in Luxembourg were not associated with treatment, prophylaxis or stockpiling of oseltamivir. Following initial local seeding, oseltamivir-resistant strains spread synchronously to sensitive strains causing a similar epidemiology and clinical symptoms.