A feasible method of improving the quantum yield of CdTe/CdS quantum dots by the first heating-cooling cycle and their application in cancer cell recognition

作者：Wang Jian Hao; Zhang Hai Li; Li Yong Qiang; Qian Jiao Ru; Wang Hai Qiao; Xu Ting Ting; Zhao Yuan Di^*

来源：Journal of Nanoparticle Research, 2010, 12(5): 1687-1695.

DOI：10.1007/s11051-010-9866-9

• Quantum dots
• Temperature
• Fluorescence
• Bioprobes
• Cell recognition
• Nanomedicine

In this article, water-soluble CdTe/CdS quantum dots (QDs) were synthesized in aqueous solution with captosuccinic acid as stabilizer. The absorption and fluorescence spectra showed that the as-prepared QDs had good optical properties. It was observed that the quantum yield (QY) of QDs was greatly increased after a heating-cooling cycle (from 22 to 41%). Then, the QDs were used to prepare fluorescent probes. The experiment results showed that the transferrin (Tf) could conjugate to QDs effectively and the HepG2 cells could be recognized successfully. This study is of great significance for the preparation of high-quality QDs and their applications in life science.

• 出版日期2010-6
• 单位华中科技大学