DETECTION OF QUINOLONE-RESISTANCE MUTATIONS IN SALMONELLA SPP. STRAINS OF EPIDEMIC AND POULTRY ORIGIN

作者：de Souza Roberta Barreiros; Magnani Marciane; Ferrari Rafaela Gomes; Mikito Kottwitz Luciana Bill; Sartori Daniele; Bronharo Tognim Maria Cristina; de Oliveira Tereza Cristina R M^*

来源：Brazilian Journal of Microbiology, 2011, 42(1): 211-215.

• Quinolones
• gyrA
• Quinolone Resistance Determining Region (QRDR)
• AS-PCR-RFLP

Mutations into codons Aspartate-87 (62%) and Serine-83 (38%) in QRDR of gyrA were identified in 105 Salmonella strains resistant to nalidixic acid (94 epidemic and 11 of poultry origin). The results show a high incidence of mutations associated to quinolone resistance but suggest association with others mechanisms of resistance.

• 出版日期2011-3