A rhodamine-based Hg(2 )-selective fluorescent probe in aqueous solution

作者：Zhao Minglei; Yang Xiao Feng^*; He Shenfeng; Wang Liping

来源：Chemical Papers, 2009, 63(3): 261-267.

DOI：10.2478/s11696-009-0016-8

• mercury ion
• probe
• rhodamine B
• fluorimetry

A new rhodamine-based Hg(2 )-selective fluorescent probe (I) was designed and synthesized. Compound I displays excellent selective and sensitive response to Hg(2 ) over other transition metal ions in neutral aqueous solutions. I itself is a colorless, nonfluorescent compound. Upon addition of Hg(2 ) to its solution, the thiosemicarbazide moiety of I undergoes an irreversible desulfurization reaction to form the corresponding 1,3,4-oxadiazole (II), a colorful and fluorescent product, causing instantaneous development of visible color and strong fluorescence emission. Based on this mechanism, a fluorogenic probe for Hg(2 ) was developed. The fluorescence increases linearly with the Hg(2 ) concentration up to 0.8 mu mol L(-1) with the detection limit of 9.4 nmol L(-) (3 sigma).

• 出版日期2009-6
• 单位西北大学