Updated guidelines for managing fungal diseases in hematology patients

作者：Hicheri Yosr; Toma Andrea; Maury Sebastien; Pautas Cecile; Mallek Kaci Hassina; Cordonnier Catherine^*

来源：Expert Review of Anti-Infective Therapy, 2010, 8(9): 1049-1060.

DOI：10.1586/ERI.10.85

• antifungals
• guidelines
• hematopoietic cell transplantation
• invasive fungal disease
• leukemia

Many prospective open or comparative studies have been published over the last few years on antifungals. As invasive fungal disease remains an important cause of morbidity and mortality in high-risk hematology patients, the correct use of antifungal drugs, either as prophylaxis, empirical treatment in neutropenic patients or for therapy of overt disease, is of the utmost importance. Several international or national groups, including the Infectious Diseases Society of America and the European Conference on Infections in Leukaemia, have elaborated practice guidelines to improve the correct usage of antifungals. This article summarizes these guidelines, which have very similar recommendations, and comments on their evidence base.

• 出版日期2010-9