Assessment of edema using STIR+ via 3D cardiovascular magnetic resonance imaging in patients with suspected myocarditis

作者：Jeserich Michael^*; Merkely Bela; Schlosser Pascal; Kimmel Simone; Pavlik Gabor; Achenbach Stephan

来源：Magnetic Resonance Materials in Physics Biology and Medicine, 2017, 30(3): 309-316.

DOI：10.1007/s10334-016-0603-y

• STIR
• Modified three-dimensional T2-weighted fast spin echo triple inversion recovery sequence
• Cardiovascular magnetic resonance imaging
• Myocarditis
• Left ventricular function
• Late gadolinium
• enhancement

Objective To evaluate three-dimensional T2-weighted fast spin echo triple inversion recovery sequences (STIR+) for the diagnosis of myocardial edema in patients with suspected early myocarditis after respiratory or gastrointestinal tract viral infection and at follow-up.
Materials and methods We prospectively examined 28 patients with suspected myocarditis and 37 controls matched for gender and age. An ECG-triggered STIR+ was used to cover the entire left ventricle in short-axis images with 10-mm slice thickness and no interslice gap. The global signal intensity ratio (heart muscle in relation to skeletal muscle) was calculated (global STIR+ ratio) to evaluate edema. All patients had repeat examinations at follow- up (mean interval 4.9 months, 1-12 months).
Results The mean global STIR+ ratio was 2.15 +/- 0.4 in the initial examination of patients as compared to 1.78 +/- 0.3 in controls (p < 0.0001) and 1.89 +/- 0.3 in patients at follow-up (p = 0.0001 vs. first visit). Left ventricular ejection fraction did not differ between patients and controls at baseline and at follow-up.
Conclusion We could identify a significantly higher global STIR+ ratio in patients with suspected myocarditis compared to controls, and a dynamic change during follow-up. The global STIR+ ratio may, therefore, be useful for the diagnosis of myocarditis and should be further explored.

• 出版日期2017-6
• 单位河北医科大学